Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit http://skinhelpdesk.com


Regeneron, Sanofi Eczema Drug Clears Hurdles in Big Trials

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Regeneron Pharmaceuticals Inc and Sanofi said on Friday their experimental treatment for eczema proved highly effective in two large studies, without serious side effects often seen with standard treatments for the chronic inflammatory skin disease.
Reuters Health Information

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Truth: Recent Aging Research May Cause Confusion And Gray Hair

Studies: You've got to love them. Just this week alone in the world of aging research, we learned that selfies can prematurely age your skin, sunbathing may actually be good for you, and older people who take the stairs are mentally sharper than those who wait for the elevator. Oh, and the debate was reignited over whether a nightly glass of wine is good for longevity. It's enough to make your head spin. Taking it from the top, and with a grain of salt that may or may not be good for those with hypertension: 1. Selfies cause wrinkles and age your skin. Yes, they can but no, they won't. A 26-year-old British blogger who takes at least 50 selfies a day consulted a dermatologist to see if the high-energy visible (HEV) light from her cellphone screen was causing her skin to age prematurely. Th...

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By Science - The Huffington Post

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BeneHold™ TASA™: a wound dressing for the management of skin tears

This series of 20 case studies focuses on patients with superficial skin tears treated with BeneHold™ TASA™ Thin Absorbent Wound Dressings in a primary care setting. This dressing incorporates a new technology combining the absorbency of hydrocolloid adhesives with the holding power, transparency, and thinness of acrylics. The efficacy of the dressing was evaluated in terms of wound healing, wear time achieved, ease of application and removal, pain on dressing change and patient and clinician satisfaction. BeneHold TASA dressings were found to be effective in the management of superficial skin tears. The dressing was well received by both clinicians and patients. BeneHold TASA dressings could potentially offer improved clinical benefits and time and cost savings. (Source: Wounds UK)

By Wounds UK

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Facegram – Objective quantitative analysis in facial reconstructive surgery

Publication date: June 2016
Source:Journal of Biomedical Informatics, Volume 61
Author(s): Ana Gerós, Ricardo Horta, Paulo Aguiar
Evaluation of effectiveness in reconstructive plastic surgery has become an increasingly important asset in comparing and choosing the most suitable medical procedure to handle facial disfigurement. Unfortunately, traditional methods to assess the results of surgical interventions are mostly qualitative and lack information about movement dynamics. Along with this, the few existing methodologies tailored to objectively quantify surgery results are not practical in the medical field due to constraints in terms of cost, complexity and poor suitability to clinical environment. These limitations enforce an urgent need for the creation of a new system to quantify facial movement and allow for an easy interpretation by medical experts. With this in mind, we present here a novel method capable of quantitatively and objectively assess complex facial movements, using a set of morphological, static and dynamic measurements. For this purpose, RGB-D cameras are used to acquire both color and depth images, and a modified block matching algorithm, combining depth and color information, was developed to track the position of anatomical landmarks of interest. The algorithms are integrated into a user-friendly graphical interface and the analysis outcomes are organized into an innovative medical tool, named facegram. This system was developed in close collaboration with plastic surgeons and the methods were validated using control subjects and patients with facial paralysis. The system was shown to provide useful and detailed quantitative information (static and dynamic) making it an appropriate solution for objective quantitative characterization of facial movement in a clinical environment.

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Evaluating Dermatology Residency Program Websites. Ashack, Kurt A; Burton, Kyle A; Soh, Jonathan M; Lanoue, Julien; Boyd, Anne H; Milford, Emily E; Dunnick, Cory; Dellavalle, Robert P

Background: Internet resources play an important role in how medical students access information related to residency programs.Evaluating program websites is necessary in order to provide accurate information for applicants and provide information regarding areas of website improvement for programs. To date, dermatology residency websites (D  WS) have not been evaluated.This paper evaluates dermatology residency websites based on availability of predefined measures.Methods: Using the FREIDA (Fellowship and Residency Electronic Interactive Database) Online database, authors searched forall accredited dermatology program websites. Eligible programs were identified through the FREIDA Online database and had a functioning website. Two authors independently extracted data with consensus ...

By Dermatology Online Journal

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Dermatologists reveal which foods they swear by for a healthy glow

‘Only 20 per cent of the way you age is down to genetic factors,’ says leading celebrity dermatologist Dr Neetu Nirdosh, whose client list includes Kelly Brook and Frieda Pinto. (Source: the Mail online | Health)

By the Mail online | Health

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Dr. Thomas Rea, father of leprosy treatment, dies at 86

Brooks HaysLOS ANGELES, March 6 (UPI) -- Dr. Thomas Rea, a dermatologist and a pioneer of the treatment of leprosy, died at the age of 86 in his home in California. (Source: Health News - UPI.com)

By Health News - UPI.com

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New technique for bloodless surgery to the scalp

Skin cancers such as malignant melanoma, squamous cell carcinoma, and basal cell carcinoma are common on the scalp,1 and the usual treatment is wide local excision with disease- free margins. Margins vary depending on the type of cancer, the size and depth of invasion, and the cytological findings, as described in the British Association of Dermatology guidelines.2 (Source: The British Journal of Oral and Maxillofacial Surgery)

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By The British Journal of Oral and Maxillofacial Surgery

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Skin cell imaging: How do wounds heal?

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Researchers from Duke University have developed a new imaging system using zebrafish cells to study how skin responds to disease and injury.

The project, known as Skinbow, uses genetically modified fish with skin cells that randomly produce combinations of red, green and blue fluorescent proteins.

The researchers performed a fin amputation then watched as existing cells migrated rapidly from surrounding skin to cover the wound, supplement the coverage, and finally expand to provide more cover. 

“One of the barriers to studying regeneration has been to visualize it at high resolution, examining what individual cells are doing and what a large number of cells are doing collectively,” cell biologist Kenneth Poss told Financial Times Magazine. “We can catch all of that with this kind of imaging.”

The research could also help scientists study the effects of infection, cancer and drugs on skin tissues.

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By jhocter

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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.

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Bell Raj Eapen
Hamilton, ON
Canada