Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit

SAHA Syndrome

Today I will post some details about SAHA syndrome which I feel is relatively common here.
Seborrhoea, acne, hirsutism and alopecia or SAHA syndrome predominantly occurs in young and middle-aged women. In addition to its association with polycystic ovaries, the condition can also be associated with infertility, cystic mastitis and obesity.

Four types are described
(1) idiopathic,
(2) ovarian,
(3) adrenal, and
(4) hyperprolactinemic SAHA.
The HAIRAN syndrome has been currently described as a fifth variant with polyendocrinopathy.

The patient needs a hormonal screen (testosterone [free and total], DHEAS, androstenedione, LH:FSH ratio) and screening for insulin resistance and fasting lipid profile. Management strategies include a low glycaemic index diet, exercise and metformin.
[Summary (SLISE)  ] Dermatology Triples* on DermKnowledgeBASE ]

Ref: Prof Dedee Murrell's article here.


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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.


Bell Raj Eapen
Hamilton, ON