Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit

Erythema Multiforme due to Herpes Labialis.

Herpes Labialis (Herpes Simplex Virus infection on the lips) may some times result in erythema multiforme minor with target lesions. In this patient lesion 1 is the healing herpes lesion and lesions 2 are due to erythema multiforme.

The mucosal involvement gives the appearance of Stevens-Johnson syndrome. Erythema multiforme is a mild, self-limited, often recurrent condition, whereas Stevens-Johnson syndrome is a severe, potentially life-threatening reaction. In the past, the two forms were believed to represent ends of a spectrum of disease, but now both are regarded as distinct entities. Stevens-Johnson syndrome is usually related to medication use.

Recurrent episodes, single mucosal involvement, lack of drug history and evidence of herpes labialis indicates that the patient is having EM Minor and is unlikely to proceed to the severe form in spite of mucosal involvement.
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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.


Bell Raj Eapen
Hamilton, ON