Skin Deep - A Dermatology Blog

Skin Deep is a blog created for dermatologists to allow free flow of information on topics and events relating to dermatology. Having comments on-line also has the advantage of allowing for further discussion and clarification if needed on various topics. However it is left to the reader to filter and judge the value of the comments. As the archives continue to accumulate, probably at some point they will become a useful reference for all. Contact Dr Bell Eapen for details.

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Sunday, November 06, 2011

Fountain of Youth

All cosmetic dermatologists use chemical peels as an anti-ageing service. Chemical peel removes superficial dead cells which will be replaced by younger cells from below. But did you know that the same principle can be applied to internal tissues as well?!


Darren J. Baker, PhD, from the Mayo Clinic in Rochester, and colleagues biomarked senescent cells in mice and then zapped the cells with drugs. They found that eliminating these cells delayed the onset of age-related pathologies associated with adipose tissue (wrinkles), skeletal muscle (muscle loss) and the eyes (cataracts) where senescent cells tend to accumulate.

"Our proof-of-principle experiments demonstrate that therapeutic interventions to clear senescent cells or block their effects may represent an avenue for treating or delaying age-related diseases and improving healthy human lifespan," the researchers concluded.

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