Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit http://skinhelpdesk.com


Future of Laser Skin Rejuvenation

Selective photothermolysis is or rather used to be dogmatic in cutaneous laser systems. Basically laser of a particular wavelength is selectively absorbed by a 'chromophore' that gets heated up. Melanin is the chromophore for hair removal and hemoglobin for blood vessels. What is the chromophore for skin rejuvenation?

For non-specific tissue heating as in skin rejuvenation systems do not have a specific chromophore! But till recently we have been on the lookout for the 'ideal' wavelength. Er-YAG, Er-Glass, CO2 all have been tried with limited success though the fractional technology has improved the safety profile considerably.
English: laser beam quality - M2 definition
Laser beam quality - M2 definition (Photo credit: Wikipedia)

Innovations happen when dogmas are challenged!

Scientists from Philips Research in Eindhoven have prototyped a system that do not depend on selective photothermolysis and hence not on any specific chromphore/wave length. The new system uses advanced optics to focus a laser beam below the epidermis. High laser intensity at the focal point induces a little known (to me) phenomenon called 'Light Induced Optical Breakdown' (LIOB) creating a mini 'explosion' along a short distance!

Graph showing the history of maximum laser pul...
Graph showing the history of maximum laser pulse intensity throughout the past 40 years. (Photo credit: Wikipedia)
This conceptually different system has many advantages. Since it uses a converging beam, the laser intensity on the surface is very less and hence the surface changes and pain are virtually nil. However the sub-epidermal effect is similar to or probably more than ablative systems. So you end up giving ablative results at no pain and no downtime.

This should bring a paradigm shift in the present selective photothermolytic systems.

I give full five peels for this technology.
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Light Induced Optical Breakdown based skin rejuvenation Laser technology from Philips
Reviewed by Bell Eapen on .
Scientists from Philips Research in Eindhoven have prototyped a new system that does not depend on selective photothermolysis.
Scientists from Philips Research in Eindhoven have prototyped a skin rejuvenation technology that does not depend on selective photothermolysis and hence not on any specific chromphore/wave length. This should bring a paradigm shift in the present selective photothermolytic systems.
PeelScore rating: 5

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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.

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Bell Raj Eapen
Hamilton, ON
Canada