Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit

The Twilight Saga

PRP or Platelet Rich Plasma is a recent cosmetic adaptation of an old technology with promising yet unsubstantiated clinical evidence. ie it is still in the twilight zone of clinical research and is often called  Vampire Facelift. (pun intended!). It is based on the theory that PRP is a rich source of many endogenous growth factors and cytokines that might play a role in enhancing wound healing. PRP is traditionally used in sports medicine and orthopedics but its cosmetic adaptation is based on the neoteric popularity of growth factors in this field. Growth factors could be a double edged sword in cosmetic dermatology. The following list includes the list of growth factors and cytokines present in higher concentration in PRP (courtesy wikipedia).

In the following posts I shall discuss the potential impacts (positive and negative) of these factors on skin from a cell biology perspective. I have no preconceived ideas at this stage neither have I explored them before. Together let us traverse this uncertain twilight zone. Perhaps we may be able to solve the mystery of PRP and who knows many other mysteries as well! BTW did you check out DermKnowledgeBASE?

Read all articles in this series on PRP.

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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.


Bell Raj Eapen
Hamilton, ON