Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit

Opposite Poles

Have you ever had this dream? Patients sitting outside your office waiting for their monthly infusion of stem cells. The polygel electrode of your next-gen skin rejuvenator not only replenishes the skin stem cell reserve but also removes any degraded cell fragments. Well, sit tight. This ‘fountain of youth’ technology may be just around the corner!

Like tiny crawling compass needles, whole living cells and cell fragments orient and move in response to electric fields - but in opposite directions, scientists at the University of California, Davis, have found.[1] This technology could open up new ways to safely and effectively deliver stem cells and remove unwanted cell fragments.
Cell Biology
Cell Biology (Photo credit: ex_magician)

Another study explores the usefulness of human in vitro models to understand the mechanisms of skin ageing.[2] They have successfully used UVA-irradiated dermal fibroblasts to investigate the anti-ageing effects of sargachromanol E isolated from a marine brown alga, Sargassum horneri.


1. "Opposites attract: How cells and cell fragments move in electric fields." 2013. 7 May. 2013 <>

2. Kim, JA. "The chromene sargachromanol E inhibits ultraviolet A-induced ..." 2012. <>

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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.


Bell Raj Eapen
Hamilton, ON