Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit http://skinhelpdesk.com


Cutaneous Manifestations of Ebola Virus Infection

English: Ebola Hemorrhagic Fever fistribution ...
Ebola Hemorrhagic Fever distribution map of outbreaks in Africa (Photo credit: Wikipedia)
Ebola epidemic was never recognized initially in West Africa as the number of deaths was insignificant compared to more mundane causes such as diarrhea and malnutrition. However an American causality in July 2014 made the word take cognizance of the emerging disaster.

Ebolavirus belonging to the Filoviridae family is one of the most virulent human pathogen causing fulminant hemorrhagic fever with a fatality rate of upto 90%! Fruit bats are the likely reservoir, and human infection occurs through contact with bats or infected animal carcasses or by person-to-person contact (through body fluids, medical care, and burial practices)

Cutaneous manifestations are never prominent but may aid diagnosis. The common cutaneous manifestations are a measles like maculo-papular rash predominantly distributed on the upper arms, flexor surface of the forearms and upper legs. The rash usually starts on the 5th – 6th day subsiding with desquamation after 2 weeks. Desquamation is prominent over the palms and soles. Purpuric or petechial rashes and red eye are also common. Jaundice may be seen in very severe cases with multi-organ failure. Immunohistochemical examination of skin biopsy can confirm diagnosis.

An experimental Ebola vaccine called VSV-EBOV was developed in the Canadian city of Winnipeg recently that offers some hope to the victims. The VSV-EBOV vaccine will be offered to West Africa, though it is untested in humans considering the extraordinary circumstances. The Ebola research in Winnipeg was led by Dr Heinz Feldmann.
Please share to see a summary of 50 recent pubmed articles on Ebola Virus Infection.

Labels: , , , , , ,



Post a Comment

All comments, questions and criticisms welcome. Relevant comments with hyperlinks will be accepted. Though this form is not CommentLuv enabled, interesting and useful comments will be acknowledged with DoFollow links in the body of the post. Irrelevant comments and spam will be deleted.

Links to this post:

Create a Link

<< Home

About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.

Address

Bell Raj Eapen
Hamilton, ON
Canada