|Image Credit Meghan @ Flikr (Image altered and text added)|
Photodynamic therapy (PDT) takes light therapy to a new level, producing better results but with more side effects. http://t.co/OtMgKsEOse
— Acne.org (@AcneOrg) September 29, 2014
A recent study published in JAAD* proposes Chlorophyll-a as the superior photosensitizer that we were waiting for. Chlorophyll-a is apparently much safer that ALA and MAL and has the following advantages:
Chlorophyll-a has intrinsic photosensitizer characteristics and does not need prior activation. Hence, the onset of action is fast.
Chlorophyll-a undergoes spontaneous permanent degradation with no risk of prolonged photosensitivity.
Chlorophyll-a is cheaper than ALA and MAL
Please share/like below to read the fourth advantage:
Last but not the least, the study establishes the safety of chlorophyll-a on dark asian skin.
The histological changes following PDT showed a sustained decrease in pilosebaceous units. Hence Chlorophyll-a PDT may be as sustainable as isotretinoin in preventing recurrence. The combination of blue and red lights are used for activation. The study shows good promise for Chlorophyll-a PDT to emerge as a sustainable and effective treatment for recalcitrant acne.
*Byong Han Song, Dong Hun Lee, Byung Chul Kim, Sang Hyeon Ku, Eun Joo Park, In Ho Kwon, Kwang Ho Kim, Kwang Joong Kim, Photodynamic therapy using chlorophyll-a in the treatment of acne vulgaris: A randomized, single-blind, split-face study, Journal of the American Academy of Dermatology, Volume 71, Issue 4, October 2014, Pages 764-771, ISSN 0190-9622.
Keywords: acne vulgaris; chlorophyll-a; light-emitting diode; photodynamic therapy; photosensitizer; treatment