Skin Deep - Clinical & Cosmetic Dermatology Blog

Skin Deep is a blog for dermatologists and skin care professionals with focus on theoretical, cosmetic and aesthetic dermatology. This blog is associated with ‘Dermatologists Sans Borders’ one of the largest curated groups of skin care professionals on facebook. If you are looking for non-technical information, please visit

Clinical Trial Assessment Scale for Cosmetic Dermatology

Clinical trials in cosmetic dermatology have some intrinsic limitations. Some of the prerequisites of an RCT such as blinding, allocation concealment and even randomization is difficult to achieve in cosmetic dermatology. Hence some of the well known scales for the methodological assessment of clinical trials such as Jadad and CONSORT have limited relevance in cosmetic clinical trial. Flawed evaluation of clinical trial quality allows flawed trials to thrive leading to clever new ways to distort trial results toward a favoured outcome.

Image Credit: By Evil Erin (

I have tried to enumerate well known biases in cosmetic dermatology and to put these ideas together as a framework for evaluating clinical trials in cosmetic dermatology. I have given it the acronym TASCDerm.

You can read more about TASCDerm and download a PDF score sheet from Dermatologists Sans Borders. [Click Here]


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About Me

As a Dermatologist and Informatician my research mainly involves application of bioinformatics techniques and tools in dermatological conditions. However my research interests are varied and I have publications in areas ranging from artificial intelligence, sequence analysis, systems biology, ontology development, microarray analysis, immunology, computational biology and clinical dermatology. I am also interested in eHealth, Health Informatics and Health Policy.


Bell Raj Eapen
Hamilton, ON